The presumption is rationally related to the proliferation of herbal-based alternative treatment without going through scientific clinical trials. The rise of herbal products that can not be accounted for potential therapeutic and side effects does not mean that all natural products redundant. In fact, many plants that save tremendous therapeutic potential when dug through scientific research.
Call it the flavonoid-giver pigment plants, which contained extensive in plants and fruits. Flavonoids are also protectors against microbial and insect attack. Wide spread of flavonoids, varieties, and low toxicity indicates that we can consume large amounts of flavonoids without worrying bad impact on health.
Flavonoids have a big role in our body as a natural biological response modifiers. Many studies have shown the role of flavonoids to modify the body's reaction to the disease. Flavonoids can reduce inflammation (inflammation), control blood sugar levels, improve immune response against cancer, and protection against heart disease.
Levels and types of flavonoids vary in each type of plant. The combination of variety and quantity of flavonoids that can be used to treat various types of diseases.
With scientific research, we can understand and get information on mechanisms to modify the cellular and metabolic signals, understanding the dose and combination therapy best for certain medications.
Inflammation
Cancer is an inflammatory disease. When the body produces inflammation in response to injury or infection, will be produced substrate that can also affect the growth of cancer.
If there is chronic inflammation, such as ulcers caused by bacteria in the stomach, the consequences are not only triggered the cancer, but also triggers its growth.
Flavonoids play a role in the fight against cancer as: anti-inflammatory (anti-inflammatory), anticancer, by stimulating apoptosis (programmed cell death), antimetastasis (antipenyebaran cancer), Antiangiogenesis (antipertumbuhan new blood vessels), improved working chemotherapy, and reduce the toxicity of chemotherapy
With chemotherapy, solid cancer cure rate (solid) such as breast, ovarian, kidney, prostate, bone, and brain in adults 2.3 percent. The low numbers prompted resistance to chemotherapeutic drugs (multi-drug resistance). Membrane transport proteins ABCG2/BCRP1 lower intracellular concentration of chemotherapy such as ironotecan and doxorubicin.
ABCG2 protein is found in large numbers of stem cells in cancer. Proteins that trigger cancer cells to stem cells to initiate tumor growth pascakemoterapi. Inhibit ABCG2 substrate increases kemosensitivitas stem cells to cancer cells to chemotherapy and improve response.
Various types of flavonoids inhibit ABCG2. Collaboration variety of flavonoids such as apigenin, luteolin, quercetin, genistein, and kaempferol inhibited the growth of cancer cells in ovarian cancer in a study in vitro (80 percent cure rate). Flavonoids are potentially inhibit the VEGF (Vascular Endothelial Growth Factor)-factor trigger angiogenesis (growth of new blood vessels in cancer.) Green tea has the potential to inhibit MMP2 (Matrix Metalloprotein 2) and MMP9 (Matrix Metalloprotein 9).
To obtain better treatment outcomes, the combination of flavonoids, green tea extract pure, and chemotherapy is an option that can be tried. The combination of natural therapy and chemotherapy gives better results because it works on different lines so it can kill as well as not giving an opportunity to grow the return of cancer cells.
Chemotherapy can kill cancer cells, but are powerless against the immunity to the drugs, nor has the potential to prevent the spread of cancer to other organs, including new blood vessel growth as a supplier of food for the growth of cancer cells.
To boost the cure rate, based on his best treatment option suppresses the growth of new blood vessels (angiogenesis), mitosis (cell division), and spread to other organs (metastasis).
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